Qwen · 122B · MoE

Can you run Qwen3.5 122B-A10B Instruct locally?

Qwen3.5 122B-A10B Instruct is a mixture-of-experts model with 122B parameters, 10B active per token. At 4-bit or better it runs on 19 of the 120 hardware configurations listed here; the smallest is the RTX PRO 6000 Blackwell (96 GB). On a 128 GB DGX Spark it runs at Q4_K_M, at roughly 25 tokens per second (our est.).

Data as of 2 November 2026

Fastest machines for Qwen3.5 122B-A10B Instruct

Every machine that runs it, fastest first. Filter by type; your machine is marked. Compare machines running it side by side

  1. 1RTX PRO 6000 BlackwellGraphics card · 96 GB~161 tok/s ModelFit est.Q4_K_M · 75 of 95 GB
  2. 22x RTX PRO 6000 BlackwellGraphics card · 192 GB~154 tok/s ModelFit est.Q4_K_M · 75 of 190 GB
  3. 3M5 UltraMac · 256–512 GB · 3 variants~102 tok/s ModelFit est.Q4_K_M · 75 GB
  4. 4M3 UltraMac · 256–512 GB · 3 variants~69 tok/s ModelFit est.Q4_K_M · 75 GB
  5. 5M2 UltraMac · 128–192 GB · 4 variants~62 tok/s ModelFit est.Q4_K_M · 75 GB
  6. 6M5 Max · 128 GB · 40cMac · 128 GB~59 tok/s ModelFit est.Q4_K_M · 75 of 96 GB
  7. 7M1 UltraMac · 128 GB · 2 variants~56 tok/s ModelFit est.Q4_K_M · 75 GB
  8. 8M4 Max · 128 GB · 40cMac · 128 GB~50 tok/s ModelFit est.Q4_K_M · 75 of 96 GB
  9. 9M3 Max · 128 GB · 40cMac · 128 GB~39 tok/s ModelFit est.Q4_K_M · 75 of 96 GB
  10. 10DGX Spark (GB10)AI mini PC · 128 GB~25 tok/s our est.Q4_K_M · 75 of 122 GB
  11. 11Ryzen AI Max+ 395 · 128 GBAI mini PC · 128 GB~23 tok/s ModelFit est.Q4_K_M · 75 of 96 GB
Too big for 101 machines

M5 Ultra · 96 GB · 80c, M5 Ultra · 96 GB · 64c, M3 Ultra · 96 GB · 80c, M3 Ultra · 96 GB · 60c, M2 Ultra · 96 GB, M3 Max · 96 GB · 30c, M2 Max · 96 GB · 38c, 2x RTX 5090, Ryzen AI Max+ 395 · 64 GB, M2 Ultra · 64 GB · 76c, M2 Ultra · 64 GB · 60c, M1 Ultra · 64 GB · 64c, M1 Ultra · 64 GB · 48c, M5 Max · 64 GB · 40c, M4 Max · 64 GB · 40c, M3 Max · 64 GB · 40c, M2 Max · 64 GB · 38c, M2 Max · 64 GB · 30c, M1 Max · 64 GB · 32c, M1 Max · 64 GB · 24c, M5 Pro · 64 GB · 20c, M5 Pro · 64 GB · 16c, M4 Pro · 64 GB · 20c, M4 Pro · 64 GB · 16c, 2x RTX 4090, 2x RTX 3090 Ti, 2x RTX 3090, 2x RX 7900 XTX, M5 Max · 48 GB · 40c, M4 Max · 48 GB · 40c, M3 Max · 48 GB · 40c, M5 Pro · 48 GB · 20c, M5 Pro · 48 GB · 16c, M4 Pro · 48 GB · 20c, M4 Pro · 48 GB · 16c, RTX 5090, M5 Max · 36 GB · 32c, M4 Max · 36 GB · 32c, M3 Max · 36 GB · 30c, M3 Pro · 36 GB, RTX 4090, RTX 3090 Ti, RTX 3090, RX 7900 XTX, M2 Max · 32 GB · 38c, M2 Max · 32 GB · 30c, M1 Max · 32 GB · 32c, M1 Max · 32 GB · 24c, M2 Pro · 32 GB, M1 Pro · 32 GB, M6 · 32 GB · 12c, M5 · 32 GB · 10c, M5 · 32 GB · 8c, M4 · 32 GB, RX 7900 XT, M5 Pro · 24 GB · 20c, M5 Pro · 24 GB · 16c, M4 Pro · 24 GB · 20c, M4 Pro · 24 GB · 16c, M6 · 24 GB · 12c, M6 · 24 GB · 10c, M5 · 24 GB · 10c, M5 · 24 GB · 8c, M4 · 24 GB, M3 · 24 GB, M2 · 24 GB, RTX 5080, RTX 5070 Ti, RTX 5060 Ti, RTX 4080 SUPER, RTX 4080, RTX 4070 Ti SUPER, RTX 4060 Ti, Tesla T4, Tesla P100, RX 9070 XT, RX 9060 XT, M3 Pro · 18 GB, RTX 5070, RTX 4070 Ti, RTX 4070 SUPER, RTX 4070, RTX 3060, M2 Pro · 16 GB, M1 Pro · 16 GB, M6 · 16 GB · 12c, M6 · 16 GB · 10c, M5 · 16 GB · 10c, M5 · 16 GB · 8c, M4 · 16 GB, M3 · 16 GB, M2 · 16 GB, M1 · 16 GB, RTX 5060, RTX 4060, RTX 3070, RTX 3060 Ti, RTX 2070, M3 · 8 GB, M2 · 8 GB, M1 · 8 GB. Qwen3.5 122B-A10B Instruct needs about 75 GB at its smallest build.

Speeds are single-user decode estimates, not measurements. "ModelFit est." comes from ModelFit's model fitted on published runs (CC BY 4.0); "our est." is memory bandwidth divided by bytes read per token, times 0.55. Memory is what the best build needs, against what the machine can give a model. Method

About the model

Parameters
122B
Active per token
10B
Type
Mixture of experts
Good for
Frontier-level reasoning, Complex tasks

Builds and how to run them

QuantizationLoadMin. RAMCommand
Q4_K_M72 GB96 GBollama run qwen3.5:122b-a10b

Load, minimum RAM and Ollama commands: ModelFit, CC BY 4.0. Load is memory with the model loaded, before long contexts.

Questions

Can I run Qwen3.5 122B-A10B Instruct on a Mac?

Yes on a Mac with enough memory: the smallest Apple configuration listed here that runs it at 4-bit or better is the M2 Ultra · 128 GB · 76c.

How much memory does Qwen3.5 122B-A10B Instruct need?

About 75 GB at the smallest build in our data, including a margin for the runtime and an 8K-token context. Longer contexts need more.

Does Qwen3.5 122B-A10B Instruct run on a DGX Spark?

Yes, at Q4_K_M. The Spark has 128 GB of unified memory, about 121.6 GB usable.